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Literature summary extracted from

  • Elson, S.W.; Baggaley, K.H.; Davison, M.; Fulston, M.; Nicholson, N.H.; Risbridger, G.D.; Tyler, J.W.
    The identification of three new biosynthetic intermediates and one further biosynthetic enzyme in the clavulanic acid pathway (1993), J. Chem. Soc. Chem. Commun., 1993, 1212-1214.
No PubMed abstract available

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.22 Mn2+ enhances activity Streptomyces clavuligerus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.3.22 33000
-
 x * 33000, SDS-PAGE Streptomyces clavuligerus

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.22 Streptomyces clavuligerus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.5.3.22 amidinoproclavaminate + H2O = proclavaminate + urea mechanism Streptomyces clavuligerus
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.22 deoxyguanidinoproclavaminic acid + H2O hydrolyzed much less rapidly than guanidinoproclavamic acid Streptomyces clavuligerus deoxyproclavaminic acid + urea
-
 ?
3.5.3.22 guanidinoproclavaminic acid + H2O best substrate Streptomyces clavuligerus proclavaminic acid + urea natural product is 2S,3R enantiomer ?
3.5.3.22 guanidinoproclavaminic acid + H2O i.e. 3-hydroxy-5-guanidino-2-(2-oxoazetidin-1-yl)pentanoic acid, probably 2S,3R enantiomer Streptomyces clavuligerus proclavaminic acid + urea natural product is 2S,3R enantiomer ?
3.5.3.22 additional information no substrate: arginine Streptomyces clavuligerus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.3.22 ? x * 33000, SDS-PAGE Streptomyces clavuligerus