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Literature summary extracted from

  • Sunnarborg, S.W.; Hinkle, C.L.; Stevenson, M.; Russell, W.E.; Raska, C.S.; Peschon, J.J.; Castner, B.J.; Gerhart, M.J.; Paxton, R.J.; Black, R.A.; Lee, D.C.
    Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability (2002), J. Biol. Chem., 277, 12838-12845.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.86 transfection of TACE into TACE deficient cells Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.86 membrane membrane-bound Mus musculus 16020
-
3.4.24.86 membrane membrane-bound Homo sapiens 16020
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.86 Homo sapiens
-
-
-
3.4.24.86 Mus musculus
-
 mouse
-
3.4.24.86 Mus musculus
-
 EC-2, clonal Ras/Myc-immortalized fibroblast cell line
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.86
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.86 fibroblast
-
 Mus musculus
-
3.4.24.86 fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.86 BTC + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 EPR + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 HB-EGF heparin binding epidermal growth factor + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 additional information
-
 Mus musculus ?
-
 ?
3.4.24.86 additional information amphiregulin is no substrate Homo sapiens ?
-
 ?
3.4.24.86 pro-TGF-alpha + H2O
-
 Mus musculus mature growth factor
-
 ?
3.4.24.86 proTNF-alpha + H2O
-
 Mus musculus soluble TNF-alpha
-
 ?
3.4.24.86 proTNF-alpha + H2O
-
 Homo sapiens soluble TNF-alpha
-
 ?
3.4.24.86 transforming growth factor alpha + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 transforming growth factor alpha + H2O
-
 Homo sapiens ?
-
 ?