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Literature summary extracted from
- Cathepsins B and H from porcine spleen (1984), J. Biol. Chem., 259, 9874-9882.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.22.16 | 0.097 | - |
L-Arg-2-naphthylamide | similar value | Sus scrofa |  |
| 3.4.22.16 | 0.22 | - |
L-Leu-2-naphthylamide | - |
Sus scrofa | |
| 3.4.22.16 | 0.46 | - |
benzoyl-L-Arg-2-naphthylamide | - |
Sus scrofa | |
| 3.4.22.16 | 0.637 | - |
benzoyl-Arg-2-naphthylamide | - |
Sus scrofa | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.22.16 | lysosome | - |
Sus scrofa | 5764 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.22.16 | 25000 | - |
gel filtration | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.16 | Sus scrofa | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.22.16 | side-chain modification | 2 mol of glucosamine and 5 mol of mannose per mol enzyme | Sus scrofa |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.22.16 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.16 | spleen | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.22.16 | 20 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.16 | alpha-N-benzoyl-DL-arginine-beta-naphthylamide + H2O | - |
Sus scrofa | alpha-N-benzoyl-DL-arginine + beta-naphthylamine | - |
? | |
| 3.4.22.16 | L-Arg-2-naphthylamide + H2O | - |
Sus scrofa | L-Arg + 2-naphthylamine | - |
? | |
| 3.4.22.16 | L-Leu-2-naphthylamide + H2O | - |
Sus scrofa | L-Leu + 2-naphthylamine | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.22.16 | monomer | 1 * 25000, SDS-PAGE | Sus scrofa |
| 3.4.22.16 | More | N-terminal amino acid sequence | Sus scrofa |
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