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Literature summary extracted from

  • Rak, A.; Niculae, A.; Kalinin, A.; Thomä, N.H.; Sidorovitch, V.; Goody, R.S.; Alexandrov, K.
    In vitro assembly, purification, and crystallization of the Rab geranylgeranyl transferase:substrate complex (2002), Protein Expr. Purif., 25, 23-30.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.60 recombinant enzyme produced in baculovirus and Escherichia coli system Rattus norvegicus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.5.1.60
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine Rattus norvegicus this posttranslational modification is essential for the biological activity of Rab proteins S-geranylgeranyl-protein + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.60 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.60 recombinant enzyme Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine enzyme catalyses the transfer of two 20-carbon geranylgeranyl groups from geranylgeranyl diphosphate onto C-terminal cysteine residues of Rab-proteins Rattus norvegicus S-geranylgeranyl-protein + diphosphate
-
 ?
2.5.1.60 geranylgeranyl diphosphate + protein-cysteine this posttranslational modification is essential for the biological activity of Rab proteins Rattus norvegicus S-geranylgeranyl-protein + diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.60 heterodimer alpha,beta Rattus norvegicus