Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Sasai, K.; Ikeda, Y.; Fujii, T.; Tsuda, T.; Taniguchi, N.
    UDP-GlcNAc concentration is an important factor in the biosynthesis of beta1,6-branched oligosaccharides: Regulation based on the kinetic properties of N-acetylglucosaminyltransferase V (2002), Glycobiology, 12, 119-127.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.155 fusion with signal peptide from baculoviral protein to permit secretion into medium, BVVdelta73 and BVV delta188 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.155 0.13
-
 N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R with TDP-glucose Homo sapiens
2.4.1.155 0.15
-
 N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R with UDP-N-acetylglucosamine Homo sapiens
2.4.1.155 0.23
-
 N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R with UDP-glucose Homo sapiens
2.4.1.155 2.9
-
 UDP-glucose
-
 Homo sapiens
2.4.1.155 2.9
-
 TDP-glucose
-
 Homo sapiens
2.4.1.155 4
-
 UDP-N-acetylglucosamine BVVdelta188 mutant Homo sapiens
2.4.1.155 4.6
-
 UDP-N-acetylglucosamine BVVdelta73 mutant Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.155 soluble fusion with signal peptide from baculoviral protein to permit secretion into medium Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.155 70000
-
 SDS-PAGE, BVVdelta188 Homo sapiens
2.4.1.155 85000
-
 SDS-PAGE, BVVdelta73 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.155 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.155
-
 Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.155 0.0036
-
 BVVDELTA73 mutant Homo sapiens
2.4.1.155 0.004
-
 BVVDELTA188 mutant Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.155 additional information ADP-glucose, CDP-glucose and GDP-glucose do not act as glycosyl donor Homo sapiens ?
-
 ?
2.4.1.155 TDP-glucose + N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 Homo sapiens TDP + ?
-
 ?
2.4.1.155 UDP-glucose + N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 Homo sapiens UDP + ?
-
 ?
2.4.1.155 UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 Homo sapiens UDP + N-acetyl-D-glucosaminyl-1,2-(N-acetyl-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 ?