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Literature summary extracted from

  • Murakoshi, I.; Kuramoto, H.; Haginiwa, J.
    The enzymic synthesis of beta-substituted alanines (1972), Phytochemistry, 11, 177-182.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.51 additional information no inhibition by pyridoxal phosphate Citrullus lanatus subsp. vulgaris
2.5.1.52 additional information no substrate inhibition Leucaena leucocephala

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.52 O3-acetyl-L-serine + 3,4-dihydroxypyridine Leucaena leucocephala involved in biosynthesis of heterocyclic beta-substituted alanines, brings about the biosynthesis of L-mimosine 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.51 Citrullus lanatus subsp. vulgaris
-
-
-
2.5.1.52 Leucaena leucocephala
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.51 partial Citrullus lanatus subsp. vulgaris
2.5.1.52
-
 Leucaena leucocephala

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.51 seedling
-
 Citrullus lanatus subsp. vulgaris
-
2.5.1.52 seedling
-
 Leucaena leucocephala
-

Storage Stability

EC Number Storage Stability Organism
2.5.1.51 0°C, crude enzyme preparation, 25% loss of activity within 22 h Citrullus lanatus subsp. vulgaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.51 O3-acetyl-L-serine + pyrazole highly specific Citrullus lanatus subsp. vulgaris 3-(pyrazol-1-yl)-L-alanine + acetate
-
 ?
2.5.1.52 additional information no activity with O-phospho-L-serine and L-Ser Leucaena leucocephala ?
-
 ?
2.5.1.52 additional information no activity with alpha,beta-diaminopropionic acid Leucaena leucocephala ?
-
 ?
2.5.1.52 O3-acetyl-L-serine + 3,4-dihydroxypyridine
-
 Leucaena leucocephala 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate i.e. L-mimosine ?
2.5.1.52 O3-acetyl-L-serine + 3,4-dihydroxypyridine involved in biosynthesis of heterocyclic beta-substituted alanines, brings about the biosynthesis of L-mimosine Leucaena leucocephala 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.51 7.3
-
-
 Citrullus lanatus subsp. vulgaris