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Literature summary extracted from

  • Gutensohn, W.; Huber, M.; Jahn, H.
    Facilitated purification of hypoxanthine phosphoribosyltransferase (1976), Hoppe-Seyler's Z. Physiol. Chem., 357, 1379-1385.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.8 72000
-
 brain enzyme, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.8 Homo sapiens
-
-
-
2.4.2.8 Rattus norvegicus
-
 3 charge variant forms
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.8
-
 Homo sapiens
2.4.2.8
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.8 brain
-
 Rattus norvegicus
-
2.4.2.8 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.8 guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens GMP + diphosphate
-
 ?
2.4.2.8 guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Rattus norvegicus GMP + diphosphate
-
 ?
2.4.2.8 hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens IMP + diphosphate
-
 ?
2.4.2.8 hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Rattus norvegicus IMP + diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.2.8 ? x * 25000-27000, SDS-PAGE Homo sapiens
2.4.2.8 ? x * 25000-27000, SDS-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.8 additional information
-
-
 Homo sapiens
2.4.2.8 additional information
-
 3 charge variant forms with pIs of 5.6, 5.85, 5.9 Rattus norvegicus