EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.8 | acetate | slightly activating | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | acetate | slightly activating | Escherichia coli |
EC Number | General Stability | Organism |
---|---|---|
2.4.2.8 | 5-phospho-alpha-D-ribose 1-diphosphate stabilizes | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | 5-phospho-alpha-D-ribose 1-diphosphate stabilizes | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.8 | 6-aminopurine nucleotides | - |
Escherichia coli | |
2.4.2.8 | 6-aminopurine nucleotides | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | 6-Hydroxypurine nucleotides | - |
Escherichia coli | |
2.4.2.8 | 6-Hydroxypurine nucleotides | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | Ba2+ | strong | Escherichia coli | |
2.4.2.8 | Ba2+ | strong | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | Ca2+ | strong | Escherichia coli | |
2.4.2.8 | Ca2+ | strong | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | nucleotides | all free 5'-nucleotides are inhibitory, 6-OH purine nucleotides are most inhibitory, while 6-NH2 purine only at high concentrations | Escherichia coli | |
2.4.2.8 | nucleotides | all free 5'-nucleotides are inhibitory, 6-OH purine nucleotides are most inhibitory, while 6-NH2 purine only at high concentrations | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | ppGpp | strong | Escherichia coli | |
2.4.2.8 | ppGpp | strong | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | Zn2+ | strong | Escherichia coli | |
2.4.2.8 | Zn2+ | strong | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.2.8 | membrane | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 16020 | - |
2.4.2.8 | membrane | - |
Escherichia coli | 16020 | - |
2.4.2.8 | periplasm | - |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
2.4.2.8 | periplasm | - |
Escherichia coli | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.8 | Mg2+ | absolute requirement for Mg2+ or Mn2+ | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | Mg2+ | absolute requirement for Mg2+ or Mn2+ | Escherichia coli | |
2.4.2.8 | Mn2+ | absolute requirement for Mg2+ or Mn2+ | Salmonella enterica subsp. enterica serovar Typhimurium | |
2.4.2.8 | Mn2+ | absolute requirement for Mg2+ or Mn2+ | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.8 | Escherichia coli | - |
- |
- |
2.4.2.8 | Escherichia coli | - |
phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | - |
2.4.2.8 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
strain LT-2 | - |
2.4.2.8 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.8 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | - |
Escherichia coli |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.2.8 | additional information | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | additional information | - |
- |
Escherichia coli |
EC Number | Storage Stability | Organism |
---|---|---|
2.4.2.8 | -20°C, dilute aqueous purified enzyme preparation, a few weeks | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | -20°C, dilute aqueous purified enzyme preparation, a few weeks | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.8 | guanine + 5-phospho-alpha-D-ribose 1-diphosphate | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes, and catalyse the 2 reactions with different specificities | Salmonella enterica subsp. enterica serovar Typhimurium | GMP + diphosphate | - |
? | |
2.4.2.8 | guanine + 5-phospho-alpha-D-ribose 1-diphosphate | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes, and catalyse the 2 reactions with different specificities | Escherichia coli | GMP + diphosphate | - |
? | |
2.4.2.8 | hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes, and catalyse the 2 reactions with different specificities | Salmonella enterica subsp. enterica serovar Typhimurium | IMP + diphosphate | - |
? | |
2.4.2.8 | hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes, and catalyse the 2 reactions with different specificities | Escherichia coli | IMP + diphosphate | - |
? | |
2.4.2.8 | xanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | XMP + diphosphate | - |
? | |
2.4.2.8 | xanthine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Escherichia coli | XMP + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.2.8 | GPRT | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | GPRT | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | Escherichia coli |
2.4.2.8 | HPRT | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | HPRT | phosphoribosyltransferases for hypoxanthine and guanine are separate enzymes | Escherichia coli |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.2.8 | 7.9 | - |
guanine phosphoribosyltransferase | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | 7.9 | - |
guanine phosphoribosyltransferase | Escherichia coli |
2.4.2.8 | 8.4 | - |
hypoxanthine phosphoribosyltransferase | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | 8.4 | - |
hypoxanthine phosphoribosyltransferase | Escherichia coli |
2.4.2.8 | 8.6 | - |
substrate xanthine | Salmonella enterica subsp. enterica serovar Typhimurium |
2.4.2.8 | 8.6 | - |
substrate xanthine | Escherichia coli |