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Literature summary extracted from

  • Smithers, G.W.; O'Sullivan, W.J.
    Hypoxanthine phosphoribosyltransferase from human brain: purification and partial characterization (1984), Biochem. Med., 32, 106-121.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.8 24000
-
 4 * 24000, SDS-PAGE Homo sapiens
2.4.2.8 100000
-
 3 charge variant forms, native gradient gel electrophoresis Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.8 Homo sapiens
-
 3 charge variant forms
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.8
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.8 guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens GMP + diphosphate
-
 ?
2.4.2.8 hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens IMP + diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.2.8 tetramer 4 * 24000, SDS-PAGE Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.8 additional information
-
 3 charge variant forms with pIs of 5.7, 5.5 and 5.0 Homo sapiens