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Literature summary extracted from

  • Pitcher, J.; Smythe, C.; Campell, D.G.; Cohen, P.
    Identification of the 38-kDa subunit of rabbit skeletal muscle glycogen synthase as glycogenin (1987), Eur. J. Biochem., 169, 497-502.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.186 38000
-
 gel filtration, SDS-PAGE, glycogenin glucosyltransferase represents the smaller subunit of glycogen synthase Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.186 UDP-glucose + glycogenin Oryctolagus cuniculus the glycogenin subunit of glycogen synthase, EC 2.4.1.11, catalyzes this reaction, i.e. the enzyme catalyzes its own glucosylation UDP + glucosylated glycogenin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.186 Oryctolagus cuniculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.186 glycoprotein autoglycosylation Oryctolagus cuniculus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.186 separation from glycogen synthase, EC 2.4.1.11, by LiBr Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.186 skeletal muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.186 UDP-glucose + glycogenin autoglycosylation reaction Oryctolagus cuniculus UDP + glucosylated glycogenin
-
 ?
2.4.1.186 UDP-glucose + glycogenin the glycogenin subunit of glycogen synthase, EC 2.4.1.11, catalyzes this reaction, i.e. the enzyme catalyzes its own glucosylation Oryctolagus cuniculus UDP + glucosylated glycogenin
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.186 More glycogenin glucosyltransferase, MW 38 kDa, represents the smaller subunit of glycogen synthase, both enzyme form a heterodimeric complex of molar ratio 1:1 Oryctolagus cuniculus
2.4.1.186 More purified glycogenin associates as a dimer in absence of SDS, MW 64 kDa, glycerol density gradient centrifugation Oryctolagus cuniculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.186 30
-
 assay at Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.186 7
-
 assay at Oryctolagus cuniculus