Literature summary extracted from

Krenitsky, T.A.; Neil, S.M.; Miller, R.L.
Guanine and xanthine phosphoribosyltransfer activities of Lactobacillus casei and Escherichia coli. Their relationship to hypoxanthine and adenine phosphoribosyltransfer activities (1970), J. Biol. Chem., 245, 2605-2611.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.2.22	guanine	-	Lacticaseibacillus casei

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.4.2.22	0.001	-	xanthine	-	Lacticaseibacillus casei

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.22	Escherichia coli	-	-	-
2.4.2.22	Lacticaseibacillus casei	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.22	5-phospho-alpha-D-ribose 1-diphosphate + xanthine	-	Escherichia coli	9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate	-	?
2.4.2.22	5-phospho-alpha-D-ribose 1-diphosphate + xanthine	-	Lacticaseibacillus casei	9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.4.2.22	0.1	-	guanine	-	Lacticaseibacillus casei

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Release 2023.1 (January 2023)