BRENDA - Enzyme Database show

Presence of poly (ADP-ribose) polymerase and poly (ADP-ribose) glycohydrolase in the dinoflagellate Crypthecodinium cohnii

Werner, E.; Sohst, S.; Gropp, F.; Simon, D.; Wagner, H.; Kroeger, H.; Eur. J. Biochem. 139, 81-86 (1984)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.4.2.30
DNA
required
Cryptothecodinium cohnii
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.30
5-Methylnicotinamide
0.15 mM, 31% inhibition
Cryptothecodinium cohnii
2.4.2.30
Benzamide
0.15 mM, 48% inhibition
Cryptothecodinium cohnii
2.4.2.30
nicotinamide
0.15 mM, 25% inhibition
Cryptothecodinium cohnii
2.4.2.30
theophylline
0.15 mM, 62% inhibition
Cryptothecodinium cohnii
2.4.2.30
thymidine
0.15 mM, 39% inhibition
Cryptothecodinium cohnii
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.2.30
Cryptothecodinium cohnii
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.4.2.30
-
Cryptothecodinium cohnii
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.30
NAD+ + (ADP-D-ribosyl)n-acceptor
poly(ADP-ribosyl)ation of histone
637998
Cryptothecodinium cohnii
nicotinamide + (ADP-D-ribosyl)n+1-acceptor
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.4.2.30
DNA
required
Cryptothecodinium cohnii
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.4.2.30
5-Methylnicotinamide
0.15 mM, 31% inhibition
Cryptothecodinium cohnii
2.4.2.30
Benzamide
0.15 mM, 48% inhibition
Cryptothecodinium cohnii
2.4.2.30
nicotinamide
0.15 mM, 25% inhibition
Cryptothecodinium cohnii
2.4.2.30
theophylline
0.15 mM, 62% inhibition
Cryptothecodinium cohnii
2.4.2.30
thymidine
0.15 mM, 39% inhibition
Cryptothecodinium cohnii
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.4.2.30
-
Cryptothecodinium cohnii
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.30
NAD+ + (ADP-D-ribosyl)n-acceptor
poly(ADP-ribosyl)ation of histone
637998
Cryptothecodinium cohnii
nicotinamide + (ADP-D-ribosyl)n+1-acceptor
-
-
-
?