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Literature summary extracted from

  • Furneaux, H.M.; Pearson, C.K.
    Adenosine diphosphate ribose transferase from baby-hamster kidney cells (BHK-21/C13). Characterization of the reaction and product (1980), Biochem. J., 187, 91-103.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.30 ATP 5-10 mM, 20-30% stimulation Mesocricetus auratus

General Stability

EC Number General Stability Organism
2.4.2.30 unstable in absence of Mg2+ Mesocricetus auratus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.30 NEM 0.5 mM Mesocricetus auratus
2.4.2.30 nicotinamide
-
 Mesocricetus auratus
2.4.2.30 thymidine
-
 Mesocricetus auratus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.30 additional information
-
 additional information kinetics for NAD+ utilization are not Michaelis-Menten type Mesocricetus auratus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.2.30 cytosol 10% of the activity Mesocricetus auratus 5829
-
2.4.2.30 nucleus 90% of the activity. Chromatin-bound Mesocricetus auratus 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.2.30 Mg2+ divalent cation required, Mg2+ preferred to Mn2+, optimal concentration 5 mM Mesocricetus auratus
2.4.2.30 Mn2+ divalent cation required, Mg2+ preferred to Mn2+ Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.30 Mesocricetus auratus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.30 BHK-21 cell
-
 Mesocricetus auratus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.30 NAD+ + (ADP-D-ribosyl)n-acceptor
-
 Mesocricetus auratus nicotinamide + (ADP-D-ribosyl)n+1-acceptor
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.30 25
-
-
 Mesocricetus auratus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.30 8
-
-
 Mesocricetus auratus