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Literature summary extracted from

  • Ketterer, B.; Beale, D.; Meyer, D.
    The structure and multiple functions of glutathione transferases (1982), Biochem. Soc. Trans., 10, 82-84.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.18 RX + glutathione Rattus norvegicus detoxification of electrophilic products of cytochrome P-450-dependent reactions, toxic catabolite of heme, bilirubin is bound and thereby neutralized HX + R-S-glutathione
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Rattus norvegicus
-
at least 7 forms
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
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Rattus norvegicus S-2,4-dinitrophenylglutathione + HCl
-
?
2.5.1.18 RX + glutathione detoxification of electrophilic products of cytochrome P-450-dependent reactions, toxic catabolite of heme, bilirubin is bound and thereby neutralized Rattus norvegicus HX + R-S-glutathione
-
?

Subunits

EC Number Subunits Comment Organism
2.5.1.18 dimer dimer composed of two of the following subunits: Ya MW 23000, Yb MW 23500, Yc MW 25000, SDS-PAGE Rattus norvegicus