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Literature summary extracted from

  • Gu, T.J.; Gu, X.B.; Ariga, T.; Yu, R.K.
    Purification and characterization of CMP-NeuAc:GM1 (Galbeta1-4GalNAc) alpha 2-3 sialyltransferase from rat brain (1990), FEBS Lett., 275, 83-86.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.2 0.065
-
 CMP-N-acetylneuraminate pH 6.5, 37°C Rattus norvegicus
2.4.3.2 75
-
 ganglioside GM1 pH 6.5, 37°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.2 membrane
-
 Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.3.2 44000
-
 x * 44000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.2 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.3.2 glycoprotein
-
 Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.3.2
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.2 brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.3.2 0.0084
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GA1 sialylated at 61% the rate of GM1 Rattus norvegicus CMP + ganglioside GM1b
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GD1b sialylated at 120% the rate of GM1 Rattus norvegicus CMP + ganglioside GT1b
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1
-
 Rattus norvegicus CMP + ganglioside GD1
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus CMP + ganglioside GD1a i.e. ganglioside GD1a ?

Subunits

EC Number Subunits Comment Organism
2.4.3.2 ? x * 44000, SDS-PAGE Rattus norvegicus