EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.65 | membrane | - |
Homo sapiens | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | Homo sapiens | the enzyme may catalyze alpha1-3 and alpha-1,4 glycosidic linkages involved in the expression of VIM-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination. Lewis-positive individuals have an active enzyme while Lewis-negative individuals have an inactive enzyme | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.65 | Homo sapiens | P21217 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | the enzyme may catalyze alpha1-3 and alpha-1,4 glycosidic linkages involved in the expression of VIM-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination. Lewis-positive individuals have an active enzyme while Lewis-negative individuals have an inactive enzyme | Homo sapiens | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? |