EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.65 | - |
Helicobacter pylori |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | Helicobacter pylori | inactivation of the enzyme eliminates expression of all Lewis antigens | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? | |
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | Helicobacter pylori UA948 | inactivation of the enzyme eliminates expression of all Lewis antigens | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.65 | Helicobacter pylori | O32631 | - |
- |
2.4.1.65 | Helicobacter pylori UA948 | O32631 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | the enzyme appears to add fucose with a greater than 5fold preference for type II chains but still retains significant activity using type I acceptors. The addition of fucose to type II acceptors does not appear to be affected by fucosylation at other sites on the carbohydrate acceptor | Helicobacter pylori | GDP + 1,3-beta-D-galactosyl-(alpha-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? | |
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | the enzyme appears to add fucose with a greater than 5fold preference for type II chains but still retains significant activity using type I acceptors. The addition of fucose to type II acceptors does not appear to be affected by fucosylation at other sites on the carbohydrate acceptor | Helicobacter pylori UA948 | GDP + 1,3-beta-D-galactosyl-(alpha-1,4-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? | |
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | inactivation of the enzyme eliminates expression of all Lewis antigens | Helicobacter pylori | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? | |
2.4.1.65 | GDP-L-fucose + 1,3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R | inactivation of the enzyme eliminates expression of all Lewis antigens | Helicobacter pylori UA948 | GDP + 1,3-beta-D-galactosyl-(alpha-(1,4)-L-fucosyl)-N-acetyl-D-glucosaminyl-R | - |
? |