Literature summary extracted from

Eberhardt, S.; Zingler, N.; Kemter, K.; Richter, G.; Cushman, M.; Bacher, A.
Domain structure of riboflavin synthase (2001), Eur. J. Biochem., 268, 4315-4323.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.5.1.9	cloning of sequence segments of residues 1-97 and 101-213, and expression in Escherichia coli	Escherichia coli

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.5.1.9	additional information	recombinant sequence segment 1-97 forms a homodimer that can bind riboflavin, 6,7-dimethyl-8-ribityllumazine, and trifluoromethyl-substituted 8-ribityllumazine derivatives, and is required for ligand binding, recombinant sequence segment 101-213 is unstable and only partially involved in riboflavin binding	Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.5.1.9	6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine	Escherichia coli	-	riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.9	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.9	6,7-dimethyl-8-ribityllumazine + 6,7-dimethyl-8-ribityllumazine	-	Escherichia coli	riboflavin + 4-(1'-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine	-	?

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Release 2023.1 (January 2023)