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Literature summary extracted from

  • Kajihara, Y.; Yamamoto, T.; Nagae, H.; Nakashizuka, M.; Sakakibara, T.; Terada, I.
    A novel alpha-2,6-sialyltransferase: transfer of sialic acid to fucosyl and sialyl trisaccharides (1996), J. Org. Chem., 61, 8632-8635.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.1 8.1
-
 Neu5Acalpha-2,3-Galbeta-1,4-Glc
-
 Photobacterium damselae
2.4.3.1 13.6
-
 fucosyl-alpha-1,2-D-galactosyl-beta-1,4-D-glucose
-
 Photobacterium damselae

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Photobacterium damselae
-
 JT0160
-
2.4.3.1 Photobacterium damselae JT0160
-
 JT0160
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine i.e. N-acetyllactosamine Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R acceptor substrate specificity Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R sialic acid is linked to C-6 of the galactose residue Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R strictly specific for CMP-N-acetylneuraminate, forms only alpha2,6-linkages Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R acceptor substrate specificity Photobacterium damselae JT0160 CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R sialic acid is linked to C-6 of the galactose residue Photobacterium damselae JT0160 CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R strictly specific for CMP-N-acetylneuraminate, forms only alpha2,6-linkages Photobacterium damselae JT0160 CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + fucosyl-alpha-1,2-D-galactosyl-beta-1,4-D-glucose
-
 Photobacterium damselae ?
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + fucosyllactose also pyridylaminated Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-[alpha-L-fucopyranosyl-1,2]-beta-D-galactopyranosyl-1,4-D-glucopyranose
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + lactose
-
 Photobacterium damselae CMP + 6'-sialyllactose
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + lactose
-
 Photobacterium damselae JT0160 CMP + 6'-sialyllactose
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + methyl-beta-D-galactopyranoside
-
 Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-beta-D-methylgalactopyranoside
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + Neu5Acalpha-2,3-Galbeta-1,4-Glc also pyridylaminated Photobacterium damselae CMP + alpha-N-acetylneuraminyl-2,6-(Neu5Acalpha-2,3-)Galbeta-1,4-Glc
-
 ?
2.4.3.1 additional information enzyme does not recognize type I oligosaccharides Photobacterium damselae ?
-
 ?
2.4.3.1 additional information enzyme does not recognize type I oligosaccharides Photobacterium damselae JT0160 ?
-
 ?