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Literature summary extracted from

  • Stoner, G.L.; Eisenberg, M.A.
    Purification and properties of 7,8-diaminopelargonic acid aminotransferase (1975), J. Biol. Chem., 250, 4029-4036.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.62 47000
-
 2 * 47000, SDS-PAGE Escherichia coli
2.6.1.62 94000
-
 gel filtration, sucrose density gradient sedimentation Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.62 Escherichia coli
-
 regulatory mutant
-
2.6.1.62 Escherichia coli
-
 derepressed for the enzymes of biotin operon
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.62 1000fold Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6.1.62 98
-
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.62 S-adenosyl-L-methionine + 7,8-diketopelargonic acid
-
 Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate
-
 ?
2.6.1.62 S-adenosyl-L-methionine + 7-amino-8-oxononanoate
-
 Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate S-adenosyl-4-methylthio-2-oxobutanoate may be decomposed nonenzymatically to form 5'-methylthioadenosine and 2-oxo-3-butenoic acid ?
2.6.1.62 S-adenosyl-L-methionine + 7-amino-8-oxononanoate
-
 Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate synonym: 7,8-diaminopelargonic acid ?
2.6.1.62 S-adenosyl-L-methionine + 8-amino-7-oxononanoate no substrates: S-adenosyl-L-ethionine, S-adenosyl-L-homocysteine, S-adenosyl-L-(2-4-methylthio)butyric acid, S-methyl-L-methionine, adenosine, methionine Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate S-adenosyl-4-methylthio-2-oxobutanoate may be decomposed nonenzymatically to form 5'-methylthioadenosine and 2-oxo-3-butenoic acid ?
2.6.1.62 S-adenosyl-L-methionine + 8-amino-7-oxononanoate no substrates: S-adenosyl-L-ethionine, S-adenosyl-L-homocysteine, S-adenosyl-L-(2-4-methylthio)butyric acid, S-methyl-L-methionine, adenosine, methionine Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate synonym: 7,8-diaminopelargonic acid ?
2.6.1.62 S-adenosyl-L-methionine + 8-amino-7-oxononanoate synonym: 7-keto-8-aminopelargonic acid, KAPA Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate S-adenosyl-4-methylthio-2-oxobutanoate may be decomposed nonenzymatically to form 5'-methylthioadenosine and 2-oxo-3-butenoic acid ?
2.6.1.62 S-adenosyl-L-methionine + 8-amino-7-oxononanoate synonym: 7-keto-8-aminopelargonic acid, KAPA Escherichia coli S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate synonym: 7,8-diaminopelargonic acid ?

Subunits

EC Number Subunits Comment Organism
2.6.1.62 dimer 2 * 47000, SDS-PAGE Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.62 pyridoxal 5'-phosphate cofactor Escherichia coli