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Literature summary extracted from

  • Fu, M.; Nikolic, D.; Van Breemen, R.B.; Silverman, R.B.
    Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid (1999), J. Am. Chem. Soc., 121, 7751-7759.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.19 (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid mechanism-based inactivator, reacts via aromatization mechanism Sus scrofa
2.6.1.19 vigabatrin mechanism Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.19 Sus scrofa
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.19 (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid + 2-oxoglutarate mechanism-based inactivator that partly undergoes inactivation Sus scrofa 4-oxo-4,5-dihydro-2-thiophenecarboxylic acid + L-glutamate
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