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Literature summary extracted from

  • Schousboe, A.; Wu, J.Y.; Roberts, E.
    Subunit structure and kinetic properties of 4-aminobutyrate-2-ketoglutarate transaminase purified from mouse brain (1974), J. Neurochem., 23, 1189-1195.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.19 2-oxoadipic acid
-
 Mus musculus
2.6.1.19 3-Mercaptopropionic acid
-
 Mus musculus
2.6.1.19 acetic acid
-
 Mus musculus
2.6.1.19 adipic acid
-
 Mus musculus
2.6.1.19 Ba2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Butyric acid
-
 Mus musculus
2.6.1.19 Ca2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Cd2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Co2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Cu2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 dioxan 5% v/v Mus musculus
2.6.1.19 Divalent metal ions with decreasing efficiency: Hg2+, Cd2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 ethanol 10% v/v, weak Mus musculus
2.6.1.19 glutamic acid
-
 Mus musculus
2.6.1.19 HgCl2 strong, 50% inhibition at 0.007 mM Mus musculus
2.6.1.19 hydrazine
-
 Mus musculus
2.6.1.19 hydroxylamine
-
 Mus musculus
2.6.1.19 methanol 10% v/v, weak Mus musculus
2.6.1.19 Mg2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Mn2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 Ni2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
2.6.1.19 p-chloromercuribenzoate strong Mus musculus
2.6.1.19 pimelic acid
-
 Mus musculus
2.6.1.19 propionic acid
-
 Mus musculus
2.6.1.19 SH-group reagents
-
 Mus musculus
2.6.1.19 Sr2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.19 53000
-
 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus
2.6.1.19 58000
-
 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.19 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.19 brain
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.19 4-aminobutanoate + 2-oxoglutarate
-
 Mus musculus 4-oxobutanoate + L-glutamate
-
 r

Subunits

EC Number Subunits Comment Organism
2.6.1.19 dimer 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.6.1.19 0.013
-
 3-Mercaptopropionic acid
-
 Mus musculus