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Literature summary extracted from

  • Casin, I.; Bordon, F.; Bertin, P.; Coutrot, A.; Podglajen, I.; Brasseur, R.; Collatz, E.
    Aminoglycoside 6'-N-acetyltransferase variants of the Ib type with altered substrate profile in clinical isolates of Enterobacter cloacae and Citrobacter freundii (1998), Antimicrob. Agents Chemother., 42, 209-215.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.82 additional information Enterobacter cloacae involved in resistance to antibiotics ?
-
 ?
2.3.1.82 additional information Citrobacter freundii involved in resistance to antibiotics ?
-
 ?
2.3.1.82 additional information Citrobacter freundii CFr564 involved in resistance to antibiotics ?
-
 ?
2.3.1.82 additional information Enterobacter cloacae EC 1562 involved in resistance to antibiotics ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.82 Citrobacter freundii
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 enzyme variant with Ser119
-
2.3.1.82 Citrobacter freundii CFr564
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 enzyme variant with Ser119
-
2.3.1.82 Enterobacter cloacae
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 and strain EC1563, enzyme variant with Ser119, cinical isolates
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2.3.1.82 Enterobacter cloacae EC 1562
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 and strain EC1563, enzyme variant with Ser119, cinical isolates
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.82 acetyl-CoA + amikacin the enzyme variant of enzyme type Ib has at position 119 a Ser instead of the Leu, conferring resistance to amikacin Enterobacter cloacae CoA + N6'-acetylamikacin
-
 ?
2.3.1.82 acetyl-CoA + amikacin the enzyme variant of enzyme type Ib has at position 119 a Ser instead of the Leu, conferring resistance to amikacin Citrobacter freundii CoA + N6'-acetylamikacin
-
 ?
2.3.1.82 acetyl-CoA + amikacin the enzyme variant of enzyme type Ib has at position 119 a Ser instead of the Leu, conferring resistance to amikacin Citrobacter freundii CFr564 CoA + N6'-acetylamikacin
-
 ?
2.3.1.82 acetyl-CoA + amikacin the enzyme variant of enzyme type Ib has at position 119 a Ser instead of the Leu, conferring resistance to amikacin Enterobacter cloacae EC 1562 CoA + N6'-acetylamikacin
-
 ?
2.3.1.82 additional information involved in resistance to antibiotics Enterobacter cloacae ?
-
 ?
2.3.1.82 additional information involved in resistance to antibiotics Citrobacter freundii ?
-
 ?
2.3.1.82 additional information involved in resistance to antibiotics Citrobacter freundii CFr564 ?
-
 ?
2.3.1.82 additional information involved in resistance to antibiotics Enterobacter cloacae EC 1562 ?
-
 ?