EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.82 | amikacin | substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | gentamicin | substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | netilmicin | substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | tobramycin | substrate inhibition | Staphylococcus epidermidis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.82 | 0.026 | - |
tobramycin | pH 7.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.036 | - |
amikacin | pH 7.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.077 | - |
gentamicin | pH 7.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.077 | - |
tobramycin | pH 6.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.216 | - |
tobramicin | pH 5.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.259 | - |
netilmicin | pH 7.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.297 | - |
gentamicin | pH 6.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.364 | - |
amikacin | pH 6.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.571 | - |
amikacin | pH 5.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 0.653 | - |
gentamicin | pH 5.5, 37°C | Staphylococcus epidermidis | |
2.3.1.82 | 2.44 | - |
netilmicin | pH 6.5, 37°C | Staphylococcus epidermidis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.82 | additional information | Staphylococcus epidermidis | involved in resistance to antibiotics | ? | - |
? | |
2.3.1.82 | additional information | Staphylococcus epidermidis RYC 13036 | involved in resistance to antibiotics | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.82 | Staphylococcus epidermidis | - |
RYC 13036 | - |
2.3.1.82 | Staphylococcus epidermidis RYC 13036 | - |
RYC 13036 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.82 | acetyl-CoA + amikacin | - |
Staphylococcus epidermidis | CoA + N6'-acetylamikacin | - |
? | |
2.3.1.82 | acetyl-CoA + amikacin | - |
Staphylococcus epidermidis RYC 13036 | CoA + N6'-acetylamikacin | - |
? | |
2.3.1.82 | acetyl-CoA + gentamicin | - |
Staphylococcus epidermidis | CoA + N6'-acetylgentamicin | - |
? | |
2.3.1.82 | acetyl-CoA + gentamicin | - |
Staphylococcus epidermidis RYC 13036 | CoA + N6'-acetylgentamicin | - |
? | |
2.3.1.82 | acetyl-CoA + gentamicin C | - |
Staphylococcus epidermidis | CoA + N6'-acetylgentamicin C | - |
? | |
2.3.1.82 | acetyl-CoA + gentamicin C | - |
Staphylococcus epidermidis RYC 13036 | CoA + N6'-acetylgentamicin C | - |
? | |
2.3.1.82 | acetyl-CoA + netilmicin | - |
Staphylococcus epidermidis | CoA + N6'-acetylnetilmicin | - |
? | |
2.3.1.82 | acetyl-CoA + tobramycin | - |
Staphylococcus epidermidis | CoA + N6'-acetyltobramycin | - |
? | |
2.3.1.82 | acetyl-CoA + tobramycin | - |
Staphylococcus epidermidis RYC 13036 | CoA + N6'-acetyltobramycin | - |
? | |
2.3.1.82 | additional information | involved in resistance to antibiotics | Staphylococcus epidermidis | ? | - |
? | |
2.3.1.82 | additional information | involved in resistance to antibiotics | Staphylococcus epidermidis RYC 13036 | ? | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.1.82 | 6.5 | - |
reaction with tobramycin, amikacin or gentamicin | Staphylococcus epidermidis |
2.3.1.82 | 7.5 | - |
activity with netilmicin | Staphylococcus epidermidis |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.82 | 0.00059 | - |
tobramycin | pH 7.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.0023 | - |
tobramycin | pH 6.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.00499 | - |
amikacin | pH 7.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.00647 | - |
tobramycin | pH 5.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.0087 | - |
amikacin | pH 6.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.02206 | - |
amikacin | pH 5.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.02256 | - |
gentamicin | pH 5.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.0482 | - |
gentamicin | pH 6.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.06446 | - |
netilmicin | pH 5.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.075 | - |
netilmicin | pH 6.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.079 | - |
gentamicin | pH 7.5, 37°C, substrate inhibition | Staphylococcus epidermidis | |
2.3.1.82 | 0.168 | - |
netilmicin | pH 7.5, 37°C, substrate inhibition | Staphylococcus epidermidis |