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Literature summary extracted from

  • Bauvois, B.; Cacan, R.; Fournet, B.; Caen, J.; Montreuil, J.; Verbert, A.
    Discrimination between activity of (alpha 2-3)-sialyltransferase and (alpha 2-6)-sialyltransferase in human platelets using p-nitrophenyl-beta-D-galactoside as acceptor (1982), Eur. J. Biochem., 121, 567-572.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.3.3 Ca2+
-
 Homo sapiens
2.4.3.3 dithioerythritol
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.3.3 additional information activity decreases with increasing divalent cation concentration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.3 blood platelet
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.3 CMP-N-acetylneuraminate + asialo-fetuin
-
 Homo sapiens CMP + fetuin
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + asialo-orosomucoid
-
 Homo sapiens CMP + orosomucoid
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + p-nitrophenyl-beta-D-galactoside
-
 Homo sapiens CMP + alpha-sialosyl-(2-6)-p-nitrophenyl-beta-D-galactoside
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein asialo-orosomucoid Homo sapiens CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein asialo-fetuin Homo sapiens CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.3.3 37
-
 assay at Homo sapiens
2.4.3.3 37
-
 optimal activity at Homo sapiens

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.4.3.3 20 40 about half-maximal activity at 20°C and 40°C Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.4.3.3 4
-
 t1/2: about 60 min Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.3.3 7.6
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.3.3 6.2 8.5 about half-maximal activity at pH 6.2 and 8.5 Homo sapiens