Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bergh, M.L.E.; van den Eijnden, D.H.
    Aglycon specificity of fetal calf liver and ovine and porcine submaxillary gland alpha-N-acetylgalactosaminide alpha 2 leads to 6 sialyltransferase (1983), Eur. J. Biochem., 136, 113-118.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.4.3.3 bovine serum albumin, 1 mg/ml, stabilizes purified enzyme Sus scrofa
2.4.3.3 bovine serum albumin, 1 mg/ml, stabilizes purified enzyme Ovis aries

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.3 microsome
-
 Sus scrofa
-
-
2.4.3.3 microsome
-
 Ovis aries
-
-
2.4.3.7 microsome
-
 Bos taurus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein Sus scrofa pathway of biosynthesis of glycans present in mucins CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein Ovis aries pathway of biosynthesis of glycans present in mucins CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.7 CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R Bos taurus pathway in glycoprotein biosynthesis CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.3 Ovis aries
-
-
-
2.4.3.3 Sus scrofa
-
-
-
2.4.3.7 Bos taurus
-
 calf
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.3 submaxillary gland
-
 Sus scrofa
-
2.4.3.3 submaxillary gland
-
 Ovis aries
-
2.4.3.7 liver fetal Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.3 CMP-N-acetylneuraminate + Galbeta(1-3)GalNAc-R R: protein, but not p-nitrophenol Sus scrofa CMP + Galbeta(1-3)(NeuAcalpha(2-6))GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + Galbeta(1-3)GalNAc-R R: protein, but not p-nitrophenol Ovis aries CMP + Galbeta(1-3)(NeuAcalpha(2-6))GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + GalNAc-R R: protein, but not p-nitrophenol Sus scrofa CMP + NeuAcalpha(2-6)GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + GalNAc-R R: protein, but not p-nitrophenol Ovis aries CMP + NeuAcalpha(2-6)GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein pathway of biosynthesis of glycans present in mucins Sus scrofa CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein pathway of biosynthesis of glycans present in mucins Ovis aries CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + NeuAcalpha(2-3)Galbeta(1-3)GalNAc-R R: protein, also p-nitrophenol, but with very low activity possibly due to another factor present in the fraction Sus scrofa CMP + NeuAcalpha(2-3)Galbeta(1-3)(NeuAcalpha(2-6))GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + NeuAcalpha(2-3)Galbeta(1-3)GalNAc-R R: protein, also p-nitrophenol, but with very low activity possibly due to another factor present in the fraction Ovis aries CMP + NeuAcalpha(2-3)Galbeta(1-3)(NeuAcalpha(2-6))GalNAc-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein acceptor substrate specificity Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein acceptor substrate specificity Ovis aries CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein porcine submaxillary asialo-mucin Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein porcine submaxillary asialo-mucin Ovis aries CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein ovine submaxillary asialo-mucin, with simple O-linked GalNAcalpha-Thr/Ser Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein ovine submaxillary asialo-mucin, with simple O-linked GalNAcalpha-Thr/Ser Ovis aries CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein absolute requirement for protein as the aglycon Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein absolute requirement for protein as the aglycon Ovis aries CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + submaxillary asialo-mucin porcine submaxillary asialo-mucin Sus scrofa CMP + submaxillary mucin
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + submaxillary asialo-mucin porcine submaxillary asialo-mucin Ovis aries CMP + submaxillary mucin
-
 ?
2.4.3.3 additional information no acceptor: beta-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenol Sus scrofa ?
-
 ?
2.4.3.3 additional information no acceptor: beta-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenol Ovis aries ?
-
 ?
2.4.3.3 additional information no acceptor: N-acetyl-D-galactosaminyl-p-nitrophenol Sus scrofa ?
-
 ?
2.4.3.3 additional information no acceptor: N-acetyl-D-galactosaminyl-p-nitrophenol Ovis aries ?
-
 ?
2.4.3.7 CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R pathway in glycoprotein biosynthesis Bos taurus CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
-
 ?
2.4.3.7 CMP-N-acetylneuraminate + N-alpha-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R no substrates are beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R or N-acetylgalactosylaminyl-R Bos taurus CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
-
 ?
2.4.3.7 CMP-N-acetylneuraminate + N-alpha-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R R can be a protein or p-nitrophenol Bos taurus CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.3.3 37
-
 assay at Sus scrofa
2.4.3.3 37
-
 assay at Ovis aries
2.4.3.7 37
-
 assay at Bos taurus