Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Beyer, T.A.; Rearick, J.I.; Paulson, J.C.; Prieels, J.P.; Sadler, J.E.; Hill, R.L.
    Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences (1979), J. Biol. Chem., 254, 12531-12541.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.4.3.3 glycerol, 25% w/v, stabilizes during purification Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.3 membrane bound to Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein Sus scrofa involved in the biosynthesis of oligosaccharide sequences of glycoproteins CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Bos taurus
-
-
-
2.4.3.3 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.1 colostrum
-
 Bos taurus
-
2.4.3.3 submaxillary gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-N-acetylneuraminate + asialo-transferrin
-
 Bos taurus CMP + transferrin
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R acceptor substrate specificity Bos taurus CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.1 CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R sialic acid is linked to C-6 of the galactose residue Bos taurus CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + antifreeze glycoprotein from antarctic fish Sus scrofa ?
-
 r
2.4.3.3 CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein involved in the biosynthesis of oligosaccharide sequences of glycoproteins Sus scrofa CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 ?
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein acceptor substrate specificity Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 r
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein sialyl-2,3-antifreeze glycoprotein, better than native form Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 r
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein antifreeze glycoprotein from antarctic fish Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 r
2.4.3.3 CMP-N-acetylneuraminate + R-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein ovine submaxillary asialo-mucin, with simple O-linked GalNAcalpha-Thr/Ser Sus scrofa CMP + R-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
-
 r
2.4.3.3 additional information no acceptor: human asialo-transferrin Sus scrofa ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.3.1 37
-
 assay at Bos taurus
2.4.3.3 37
-
 assay at Sus scrofa