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Literature summary extracted from

  • Doering, T.
    A unique alpha-1,3-mannosyltransferase of the pathogenic fungus Cryptococcus neoformans (1999), J. Bacteriol., 181, 5482-5488.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.1.132 pharmacology target for antifungal drug discovery Cryptococcus neoformans

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.132 GDP
-
 Cryptococcus neoformans
2.4.1.132 mannose-1-phosphate
-
 Cryptococcus neoformans
2.4.1.132 additional information not inhibited by amphomycin or tunicamycin Cryptococcus neoformans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.132 membrane
-
 Cryptococcus neoformans 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.132 additional information Cryptococcus neoformans role in the synthesis of the glucuronoxylomannan of the capsule ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.132 Cryptococcus neoformans
-
 pathogenic fungus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.132 additional information role in the synthesis of the glucuronoxylomannan of the capsule Cryptococcus neoformans ?
-
 ?