Literature summary extracted from

Milart, P.; Urbanska, E.M.; Turski, W.A.; Paszkowski, T.; Sikorski, R.
Kynurenine aminotransferase I activity in human placenta (2001), Placenta, 22, 259-261.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.6.1.7	glutamine	0.08 mM; 50% inhibition of placental KAT I	Homo sapiens
2.6.1.7	L-phenylalanine	-	Homo sapiens
2.6.1.7	L-tryptophan	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.6.1.7	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.6.1.7	placenta	KAT I	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.6.1.7	L-kynurenine + pyruvate	placental KAT I, higher activity than with 2-oxoglutarate	Homo sapiens	kynurenic acid + L-alanine + H2O	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.6.1.7	8.8	-	total placental KAT activity	Homo sapiens
2.6.1.7	9.8	-	placental KAT I activity	Homo sapiens

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Release 2023.1 (January 2023)