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Literature summary extracted from

  • Nakatani, M.; Morimoto, M.; Noguchi, T.; Kido, R.
    Subcellular distribution and properties of kynurenine transaminase in rat liver (1974), Biochem. J., 143, 303-310.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.7 1.6
-
 L-kynurenine pH 6.5, 37°C, enzyme from supernatant Rattus norvegicus
2.6.1.7 2.5
-
 L-kynurenine pH 6.5, 37°C, mitochondrial enzyme Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.7 lysosome 10% of liver total activity at pH 6.5 Rattus norvegicus 5764
-
2.6.1.7 mitochondrion
-
 Rattus norvegicus 5739
-
2.6.1.7 additional information subcellular distribution Rattus norvegicus
-
-
2.6.1.7 soluble 12% of liver total activity at pH 6.5 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.7 Rattus norvegicus
-
 Donryu
-
2.6.1.7 Rattus norvegicus Donryu
-
 Donryu
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.7 L-3-hydroxykynurenine + 2-oxoglutarate
-
 Rattus norvegicus xanthurenic acid + L-glutamate
-
 ?
2.6.1.7 L-3-hydroxykynurenine + 2-oxoglutarate
-
 Rattus norvegicus Donryu xanthurenic acid + L-glutamate
-
 ?
2.6.1.7 L-kynurenine + 2-oxoglutarate
-
 Rattus norvegicus kynurenic acid + L-glutamate + H2O
-
 ?
2.6.1.7 L-kynurenine + 2-oxoglutarate
-
 Rattus norvegicus Donryu kynurenic acid + L-glutamate + H2O
-
 ?
2.6.1.7 L-kynurenine + pyruvate
-
 Rattus norvegicus kynurenic acid + L-alanine + H2O
-
 ?
2.6.1.7 L-kynurenine + pyruvate
-
 Rattus norvegicus Donryu kynurenic acid + L-alanine + H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.7 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.7 6 6.5
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.6.1.7 6.5 8.8 maximal activity at pH 6.5, approx. half-maximal activity at pH 8.8 Rattus norvegicus