EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.3.13 | construction of a Leu4'-'lacZ fusion. The Leu4 gene encodes 2 forms: a short cytoplasmic form and a long form that is targeted to the mitochondria | Saccharomyces cerevisiae |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.3.13 | leucine | - |
Saccharomyces cerevisiae |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.3.13 | cytoplasm | the Leu4 gene encodes 2 forms: a short cytoplasmic form and a long form that is targeted to the mitochondria | Saccharomyces cerevisiae | 5737 | - |
2.3.3.13 | mitochondrion | the Leu4 gene encodes 2 forms: a short cytoplasmic form and a long form that is targeted to the mitochondria | Saccharomyces cerevisiae | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.3.13 | 65000 | - |
2 * 65000, cytoplasmic enzyme | Saccharomyces cerevisiae |
2.3.3.13 | 130000 | - |
cytoplasmic form, gel filtration | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.13 | 2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Saccharomyces cerevisiae | the cytoplasmic form is involved in Leu biosynthesis | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.3.13 | Saccharomyces cerevisiae | - |
the Leu4 gene encodes 2 forms: a short cytoplasmic form and a long form that is targeted to the mitochondria | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.13 | 2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Saccharomyces cerevisiae | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | i.e. alpha-isopropylmalate | ? | |
2.3.3.13 | 2-oxo-3-methylbutanoate + acetyl-CoA + H2O | the cytoplasmic form is involved in Leu biosynthesis | Saccharomyces cerevisiae | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.3.13 | dimer | 2 * 65000, cytoplasmic enzyme | Saccharomyces cerevisiae |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.3.13 | 0.4 | - |
leucine | - |
Saccharomyces cerevisiae |