EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | additional information | upregulated by agents activationg cAMP pathway | Sus scrofa | |
1.6.3.1 | additional information | upregulated by agents activationg cAMP pathway | Canis lupus familiaris |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.6.3.1 | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.6.3.1 | apical plasma membrane | - |
Sus scrofa | 16324 | - |
1.6.3.1 | apical plasma membrane | - |
Canis lupus familiaris | 16324 | - |
1.6.3.1 | apical plasma membrane | seven transmembrane regions found | Homo sapiens | 16324 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | Ca2+ | required for full activity | Sus scrofa | |
1.6.3.1 | Ca2+ | required for full activity | Canis lupus familiaris | |
1.6.3.1 | Ca2+ | required for full activity | Homo sapiens | |
1.6.3.1 | Ca2+ | regulates enzyme activity | Sus scrofa | |
1.6.3.1 | Ca2+ | regulates enzyme activity | Canis lupus familiaris | |
1.6.3.1 | Ca2+ | regulates enzyme activity | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.6.3.1 | 177000 | - |
calculated from DNA sequence | Sus scrofa |
1.6.3.1 | 180000 | - |
SDS-PAGE | Sus scrofa |
1.6.3.1 | 180000 | - |
SDS-PAGE | Canis lupus familiaris |
1.6.3.1 | 180000 | - |
SDS-PAGE | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.3.1 | NAD(P)H + H+ + O2 | Caenorhabditis elegans | - |
NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | Sus scrofa | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | Canis lupus familiaris | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | Homo sapiens | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.3.1 | Caenorhabditis elegans | O61213 | high sequence similarities to mammalian proteins | - |
1.6.3.1 | Canis lupus familiaris | - |
- |
- |
1.6.3.1 | Homo sapiens | Q9NRD8 | - |
- |
1.6.3.1 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.3.1 | additional information | - |
Homo sapiens | - |
1.6.3.1 | additional information | different tissues screened for ThOX2, except for a weak signal in stomach ThOX2 in exclusively found in thyroid cells | Canis lupus familiaris | - |
1.6.3.1 | stomach | very weak signal | Canis lupus familiaris | - |
1.6.3.1 | thyroid gland | - |
Sus scrofa | - |
1.6.3.1 | thyroid gland | - |
Canis lupus familiaris | - |
1.6.3.1 | thyroid gland | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.3.1 | NAD(P)H + H+ + O2 | - |
Sus scrofa | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | - |
Canis lupus familiaris | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | - |
Homo sapiens | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | - |
Caenorhabditis elegans | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Sus scrofa | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Canis lupus familiaris | NAD(P)+ + H2O2 | - |
? | |
1.6.3.1 | NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Homo sapiens | NAD(P)+ + H2O2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | FAD | - |
Sus scrofa | |
1.6.3.1 | FAD | binding site | Homo sapiens |