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Literature summary extracted from

  • Gerritsen, M.E.; Perry, C.A.
    Regulation of eicosanoid synthesis in microvessel endothelium: glucocorticoids do not affect arachidonyl CoA synthetase activity (1990), Biochim. Biophys. Acta, 1045, 174-179.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.15 0.06
-
 arachidonate
-
 Oryctolagus cuniculus
6.2.1.15 0.15
-
 CoA
-
 Oryctolagus cuniculus
6.2.1.15 0.8
-
 ATP
-
 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.15 microsome
-
 Oryctolagus cuniculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.2.1.15 Mg2+ required Oryctolagus cuniculus
6.2.1.15 Mg2+ Km: 1 mM Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.3 Oryctolagus cuniculus
-
-
-
6.2.1.15 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.3 blood vessel endothelium coronary microvessel, cell culture Oryctolagus cuniculus
-
6.2.1.15 blood vessel endothelium coronary microvessel, cell culture Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.3 ATP + oleate + CoA
-
 Oryctolagus cuniculus AMP + diphosphate + oleoyl-CoA
-
 ?
6.2.1.15 ATP + 5,8,11,14,17-eicosapentaenoic acid + CoA
-
 Oryctolagus cuniculus ATP + diphosphate + 5,8,11,14,17-eicosapentaenoyl-CoA
-
 ?
6.2.1.15 ATP + 8,11,14-eicosatrienoate + CoA
-
 Oryctolagus cuniculus AMP + diphosphate + 8,11,14-eicosatrienoyl-CoA
-
 ?
6.2.1.15 ATP + arachidonate + CoA
-
 Oryctolagus cuniculus AMP + diphosphate + arachidonoyl-CoA
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
6.2.1.15 45
-
 half-life: 0.8 min Oryctolagus cuniculus