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Literature summary extracted from

  • Tudball, N.; Thomas, P.
    Studies on the inhibition of the L-serine O-sulphate-degrading system of pig liver and the topography of its active site (1973), Eur. J. Biochem., 40, 25-29.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.10 3-Cyano-L-alanine 10 mM, 36% inhibition and 20 mM, 50% inhibition Sus scrofa
4.3.1.10 4-iodoacetamidosalicylic acid irreversible Sus scrofa
4.3.1.10 5-aminoisophthallic acid 50 mM, 19% inhibition Sus scrofa
4.3.1.10 5-bromo-2-furoic acid 10 mM, 50% inhibition Sus scrofa
4.3.1.10 aminomalonic acid 10 mM, 44% inhibition Sus scrofa
4.3.1.10 benzoic acid 34 mM, 63% inhibition Sus scrofa
4.3.1.10 D-glycerate sulfate 50 mM, 25% inhibition Sus scrofa
4.3.1.10 DL-homocysteic acid 50 mM, 21% inhibition; 50 mM, 23% inhibition Sus scrofa
4.3.1.10 hydroxybutyric acid sulfonate 50 mM, 23% inhibition Sus scrofa
4.3.1.10 isophthalic acid 10 mM, 42% inhibition Sus scrofa
4.3.1.10 L-aspartic acid 40 mM, 20% inhibition Sus scrofa
4.3.1.10 L-cysteic acid 50 mM, 25% inhibition Sus scrofa
4.3.1.10 L-cysteine S-sulfate 50 mM, 30% inhibition Sus scrofa
4.3.1.10 L-Glutamic acid 40 mM, 23% inhibition Sus scrofa
4.3.1.10 L-glycerate sulfate 40 mM, 42% inhibition Sus scrofa
4.3.1.10 lactic acid sulfonate 50 mM, 25% inhibition Sus scrofa
4.3.1.10 m-chlorobenzoate 12.5 mM, 85% inhibition Sus scrofa
4.3.1.10 m-Hydroxybenzoate 20 mM, 47% inhibition Sus scrofa
4.3.1.10 m-iodobenzoate 6.0 mM, 90% inhibition Sus scrofa
4.3.1.10 m-toluic acid 25 mM, 59% inhibition Sus scrofa
4.3.1.10 additional information
-
 Sus scrofa
4.3.1.10 O-phospho-L-serine weak non-competitive Sus scrofa
4.3.1.10 PO43- non-competitive Sus scrofa
4.3.1.10 succinic acid 40 mM, 42% inhibition Sus scrofa
4.3.1.10 terephthalic acid 50 mM, 53% inhibition Sus scrofa
4.3.1.10 trimesic acid 50 mM, 19% inhibition Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.10 50
-
 3-chloro-L-alanine methyl ester
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.10 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.1.10 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.10 3-chloro-L-alanine methyl ester
-
 Sus scrofa ?
-
 ?
4.3.1.10 L-serine O-sulfate
-
 Sus scrofa pyruvate + NH3 + sulfate
-
 ?