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Literature summary extracted from
- L-Aspartase from Escherichia coli: substrate specificity and role of divalent metal ions (1988), Biochemistry, 27, 9089-9093.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.1.1 | (1-aminopropyl)-phosphonate | - |
Escherichia coli |  |
| 4.3.1.1 | (3-aminopropyl)-phosphonate | - |
Escherichia coli | |
| 4.3.1.1 | (aminomethyl)-phosphonate | - |
Escherichia coli | |
| 4.3.1.1 | 2-hydroxy-3-nitropropionate | - |
Escherichia coli | |
| 4.3.1.1 | 3-nitropropionate | - |
Escherichia coli | |
| 4.3.1.1 | beta-aspartylhydrazine | - |
Escherichia coli | |
| 4.3.1.1 | D-2-methylmalate | - |
Escherichia coli | |
| 4.3.1.1 | D-malate | - |
Escherichia coli | |
| 4.3.1.1 | DL-2-amino-3-phosphonopropionate | - |
Escherichia coli | |
| 4.3.1.1 | DL-2-amino-4-phosphonobutyrate | - |
Escherichia coli | |
| 4.3.1.1 | DL-2-bromosuccinate | - |
Escherichia coli | |
| 4.3.1.1 | L-2-chlorosuccinate | - |
Escherichia coli | |
| 4.3.1.1 | L-malate | - |
Escherichia coli | |
| 4.3.1.1 | Mercaptosuccinate | - |
Escherichia coli | |
| 4.3.1.1 | Methylsuccinate | - |
Escherichia coli | |
| 4.3.1.1 | N-acetyl-L-aspartate | - |
Escherichia coli | |
| 4.3.1.1 | o-phospho-D-serine | - |
Escherichia coli | |
| 4.3.1.1 | Phosphoglycolate | - |
Escherichia coli | |
| 4.3.1.1 | succinate | - |
Escherichia coli | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.3.1.1 | Ca2+ | activates at pH 7.0 | Escherichia coli | |
| 4.3.1.1 | Cd2+ | activates at pH 7.0 | Escherichia coli | |
| 4.3.1.1 | Co2+ | activates at pH 7.0 | Escherichia coli | |
| 4.3.1.1 | Mg2+ | - |
Escherichia coli | |
| 4.3.1.1 | Mn2+ | activates at pH 7.0 | Escherichia coli | |
| 4.3.1.1 | additional information | - |
Escherichia coli | |
| 4.3.1.1 | Zn2+ | activates at pH 7.0 | Escherichia coli | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.3.1.1 | Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.3.1.1 | L-aspartate | r | Escherichia coli | fumarate + NH3 | - |
? | |
| 4.3.1.1 | L-aspartate | absolutely specific | Escherichia coli | fumarate + NH3 | - |
? | |
| 4.3.1.1 | L-aspartate | natural substrate | Escherichia coli | fumarate + NH3 | - |
? | |
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