Any feedback?
Literature summary extracted from
- Biosynthesis of pseudouridine in the in vitro transcribed tRNATyr precursor (1977), FEBS Lett., 77, 75-82.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.70 | additional information | Salmonella enterica subsp. enterica serovar Typhimurium | pseudouridylate synthetase I is responsible for the biosynthesis of pseudouridine in the anticodon region of several tRNA species | ? | - |
? |  |
| 4.2.1.70 | additional information | Salmonella enterica subsp. enterica serovar Typhimurium | pseudouridylate synthetase II is responsible for the biosynthesis of pseudouridine in the TpsiCG loop of every tRNA molecule | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.70 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
TA265 (wild-type strain of LT-2) | - |
| 4.2.1.70 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
TA253 (carrying the hisT 1504 mutation) | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.2.1.70 | pseudouridylate synthetase I, partial | Salmonella enterica subsp. enterica serovar Typhimurium |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.70 | additional information | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.70 | additional information | pseudouridylate synthetase I is responsible for the biosynthesis of pseudouridine in the anticodon region of several tRNA species | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
| 4.2.1.70 | additional information | pseudouridylate synthetase II is responsible for the biosynthesis of pseudouridine in the TpsiCG loop of every tRNA molecule | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
| 4.2.1.70 | uracil + D-ribose 5-phosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | pseudouridine 5'-phosphate + H2O | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
