EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.46 | TDP | - |
Saccharopolyspora erythraea | |
4.2.1.46 | TTP | - |
Saccharopolyspora erythraea |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.46 | 0.019 | - |
NAD+ | - |
Saccharopolyspora erythraea | |
4.2.1.46 | 0.034 | - |
dTDPglucose | - |
Saccharopolyspora erythraea |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.1.46 | 36000 | - |
2 * 36000, SDS-PAGE | Saccharopolyspora erythraea |
4.2.1.46 | 60000 | - |
gel filtration | Saccharopolyspora erythraea |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.46 | dTDP-glucose | Saccharopolyspora erythraea | key role in biosynthesis of macrolides and other types of antibiotics | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.46 | Saccharopolyspora erythraea | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.2.1.46 | - |
Saccharopolyspora erythraea |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.2.1.46 | 0.4 | - |
dTDPglucose | Saccharopolyspora erythraea |
EC Number | Storage Stability | Organism |
---|---|---|
4.2.1.46 | 50% loss of activity during storage at -20¦C or -80¦C for less than 1 week | Saccharopolyspora erythraea |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.46 | dTDP-glucose | - |
Saccharopolyspora erythraea | dTDP-4-dehydro-6-deoxy-D-glucose + H2O | - |
? | |
4.2.1.46 | dTDP-glucose | key role in biosynthesis of macrolides and other types of antibiotics | Saccharopolyspora erythraea | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.1.46 | dimer | 2 * 36000, SDS-PAGE | Saccharopolyspora erythraea |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.46 | 7.5 | - |
dTDPglucose, assay at | Saccharopolyspora erythraea |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.46 | NAD+ | - |
Saccharopolyspora erythraea |