EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.28 | glycerol | stereospecificity: enzyme-R-glycerol complex responsible for product-formation, enzyme-S-glycerol complex responsible for inactivation, several molecules of glycerol per enzyme molecule involved, active-site inhibition, C3-methyl group plays crucial role; suicide inactivation in vitro, reactivation possible in presence of coenzyme, Mg2+, ATP in vivo | Klebsiella pneumoniae | |
4.2.1.28 | additional information | substrate analogues | Klebsiella pneumoniae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.28 | additional information | - |
additional information | - |
Klebsiella pneumoniae | |
4.2.1.28 | 0.186 | - |
(S)-1,2-Propanediol | - |
Klebsiella pneumoniae | |
4.2.1.28 | 0.3 | - |
RS-1,2-propanediol | - |
Klebsiella pneumoniae | |
4.2.1.28 | 0.6 | - |
(R)-1,2-Propanediol | - |
Klebsiella pneumoniae | |
4.2.1.28 | 16 | - |
glycerol | - |
Klebsiella pneumoniae |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.28 | Klebsiella pneumoniae | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.28 | (R)-1,2-propanediol | - |
Klebsiella pneumoniae | propanal + H2O | - |
? | |
4.2.1.28 | (S)-1,2-propanediol | - |
Klebsiella pneumoniae | propanal + H2O | - |
? | |
4.2.1.28 | 1,2-propanediol | - |
Klebsiella pneumoniae | propanal | - |
? | |
4.2.1.28 | glycerol | - |
Klebsiella pneumoniae | beta-hydroxypropionaldehyde | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.28 | additional information | - |
additional information | glycerol analogues | Klebsiella pneumoniae | |
4.2.1.28 | 317 | - |
glycerol | - |
Klebsiella pneumoniae |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.28 | cobamide | mechanism of coenzyme action | Klebsiella pneumoniae |