Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Papadopoulos, A.I.; Walker, J.; Barrett, J.
    A novel cystathionine beta-synthase from Panagrellus redivivus (Nematoda) (1996), Int. J. Biochem. Cell Biol., 28, 543-549.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.22 beta-chloro-L-alanine
-
 Panagrellus redivivus
4.2.1.22 bithionol
-
 Panagrellus redivivus
4.2.1.22 Cd2+
-
 Panagrellus redivivus
4.2.1.22 Cu3+
-
 Panagrellus redivivus
4.2.1.22 Dichlorophene
-
 Panagrellus redivivus
4.2.1.22 Hexachlorophene
-
 Panagrellus redivivus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.22 0.13
-
 L-Cys
-
 Panagrellus redivivus
4.2.1.22 1.72
-
 2-mercaptoethanol
-
 Panagrellus redivivus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.1.22 cytosol
-
 Panagrellus redivivus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.1.22 additional information Na+, K+, Li+, Ca2+, Mg2+, Zn2+, Co2+, no effect on activity Panagrellus redivivus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.22 L-Serine + homocysteine Panagrellus redivivus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.22 Panagrellus redivivus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.22
-
 Panagrellus redivivus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.22 32
-
-
 Panagrellus redivivus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.22 L-Cysteine + 2-mercaptoethanol
-
 Panagrellus redivivus HOOC-CH(NH2)-CH2-S-CH2-CH2OH + H2S
-
 ?
4.2.1.22 L-Cysteine + DL-homocysteine
-
 Panagrellus redivivus Cystathionine + H2S
-
 ?
4.2.1.22 L-Serine + homocysteine
-
 Panagrellus redivivus Cystathionine + H2O
-
 ?
4.2.1.22 L-Serine + homocysteine
-
 Panagrellus redivivus ?
-
 ?
4.2.1.22 additional information no L-serine sulfhydrase activity Panagrellus redivivus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.22 8 9
-
 Panagrellus redivivus