Literature summary extracted from

White, P.J.; Young, J.; Hunter, I.S.; Nimmo, H.G.; Coggins, J.R.
The purification and characterization of 3-dehydroquinase from Streptomyces coelicolor (1990), Biochem. J., 265, 735-738.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.2.1.10	Cl-	no significant effect	Streptomyces coelicolor

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
4.2.1.10	0.6	-	3-dehydroquinate	-	Streptomyces coelicolor

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
4.2.1.10	16000	-	12 * 16000, SDS-PAGE	Streptomyces coelicolor
4.2.1.10	209000	-	gel filtration	Streptomyces coelicolor

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.10	Streptomyces coelicolor	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
4.2.1.10	-	Streptomyces coelicolor

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
4.2.1.10	3-dehydroquinate = 3-dehydroshikimate + H2O	the first step of the reaction involves the formation of an imine intermediate between the oxo group of the 3-dehydroquinate and the enzyme	Streptomyces coelicolor	a

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
4.2.1.10	183.2	-	-	Streptomyces coelicolor

Storage Stability

EC Number	Storage Stability	Organism
4.2.1.10	stable	Streptomyces coelicolor

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.10	3-dehydroquinate	-	Streptomyces coelicolor	3-dehydroshikimate + H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
4.2.1.10	dodecamer	12 * 16000, SDS-PAGE	Streptomyces coelicolor

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
4.2.1.10	8	-	-	Streptomyces coelicolor

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)