Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jacobson, J.W.; Hart, B.A.; Doy, C.H.; Giles, N.H.
    Purification and stability of the multienzyme complex encoded in the arom gene cluster of Neurospora crassa (1972), Biochim. Biophys. Acta, 289, 1-12.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.10 167000
-
 sucrose density gradient centrifugation Neurospora crassa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.25 shikimate + NADP+ Neurospora crassa
-
 3-dehydroshikimate + NADPH + H+
-
 ?
4.2.1.10 5-dehydroquinate Neurospora crassa enzyme is involved in the biosynthesis of aromatic amino acids ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.25 Neurospora crassa
-
 multienzyme complex
-
4.2.1.10 Neurospora crassa
-
 wild type strain 74A, multienzyme complex with the activities of ec 1.1.1.25, ec 4.2.1.10, 5-dehydroquinate synthetase, 3-enolpyruvylshikimic acid 5-phosphate synthetase and shikimic acid kinase
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.25 multienzyme complex Neurospora crassa
4.2.1.10 multienzyme complex with the activities of ec 1.1.1.25, ec 4.2.1.10, 5-dehydroquinate synthetase, 3-enolpyruvylshikimic acid 5-phosphate synthetase and shikimic acid kinase Neurospora crassa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.10 mycelium
-
 Neurospora crassa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.10 additional information
-
-
 Neurospora crassa
4.2.1.10 0.096
-
-
 Neurospora crassa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.25 shikimate + NADP+
-
 Neurospora crassa 3-dehydroshikimate + NADPH + H+
-
 ?
4.2.1.10 5-dehydroquinate
-
 Neurospora crassa dehydroshikimate + H2O 5-dehydroshikimate ?
4.2.1.10 5-dehydroquinate enzyme is involved in the biosynthesis of aromatic amino acids Neurospora crassa ?
-
 ?