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Literature summary extracted from

  • Jakubowski, H.
    The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine (1982), Biochim. Biophys. Acta, 709, 325-331.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.9 S-adenosylhomocysteine competitive with respect to ATP and valine in the ATP-diphosphate exchange reaction, noncompetitive with respect to ATP and valine and uncompetitive with respect ro tRNA in the tRNA aminoacylation Lupinus luteus

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.9 Lupinus luteus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.9 seed
-
Lupinus luteus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.9 ATP + L-valine + tRNAVal
-
Lupinus luteus AMP + diphosphate + L-valyl-tRNAVal
-
?
6.1.1.9 additional information valine-dependent ATP-diphosphate exchange: valine + ATP + enzyme /Val-AMP-enzyme + diphosphate Lupinus luteus ?
-
?