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Literature summary extracted from

  • Sato, N.; Arai, K.; Masai, H.
    Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7 (1997), EMBO J., 16, 4340-4351.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.1 expressed in COS7 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.1 cytoplasm distributed diffusibly in cytoplasm in the mitotic phase Homo sapiens 5737
-
2.7.11.1 nucleus the enzyme is localized primarily in nuclei in interphase Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.1 ATP + a protein Homo sapiens huCdc7 may regulate processes of DNA replication by modulating MCM functions ADP + a phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Homo sapiens O00311
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.1 testis transcribed most abundantly in testis Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 ATP + a protein huCdc7 may regulate processes of DNA replication by modulating MCM functions Homo sapiens ADP + a phosphoprotein
-
 ?
2.7.11.1 ATP + MCM2 wild-type huCdc7 protein expressed in COS7 cells phosphorylates MCM2 and MCM3 proteins in vitro Homo sapiens ADP + ?
-
 ?
2.7.11.1 ATP + MCM3 wild-type huCdc7 protein expressed in COS7 cells phosphorylates MCM2 and MCM3 proteins in vitro Homo sapiens ADP + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 cell division cycle 7-related protein kinase
-
 Homo sapiens