BRENDA - Enzyme Database

Deoxyribose 5-phosphate aldolase. II. Purification and properties of the rat liver enzyme

Groth, D.P.; J. Biol. Chem. 242, 155-159 (1967)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.2.4
adipate
activates
Rattus norvegicus
4.1.2.4
cis-aconitate
activates
Rattus norvegicus
4.1.2.4
citrate
no activity in absence of the activator
Rattus norvegicus
4.1.2.4
DL-isocitrate
activates
Rattus norvegicus
4.1.2.4
fumarate
activates
Rattus norvegicus
4.1.2.4
Fumarate monomethyl ester
activates
Rattus norvegicus
4.1.2.4
Glutarate
activates
Rattus norvegicus
4.1.2.4
malate
activates
Rattus norvegicus
4.1.2.4
succinate
activates
Rattus norvegicus
4.1.2.4
tricarballylate
activates
Rattus norvegicus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.2.4
0.17
-
2-deoxy-D-ribose 5-phosphate
-
Rattus norvegicus
4.1.2.4
0.2
-
D-glyceraldehyde 3-phosphate
-
Rattus norvegicus
4.1.2.4
0.267
-
acetaldehyde
-
Rattus norvegicus
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.2.4
253000
-
monomeric form, sucrose density gradient centrifugation
Rattus norvegicus
4.1.2.4
535000
-
dimeric form, sucrose density gradient centrifugation
Rattus norvegicus
4.1.2.4
700000
-
trimeric form, sucrose density gradient centrifugation
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
Rattus norvegicus
the enzyme may have an important role as a source of 2-deoxyribose 5-phosphate for deoxynucleotide synthesis in rat liver
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.2.4
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.1.2.4
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.2.4
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.1.2.4
1.775
-
-
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.2.4
2-deoxy-D-ribose 5-phosphate
-
5168
Rattus norvegicus
D-glyceraldehyde 3-phosphate + acetaldehyde
-
5168
Rattus norvegicus
-
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
-
5168
Rattus norvegicus
2-Deoxy-D-ribose 5-phosphate
-
5168
Rattus norvegicus
-
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
the enzyme may have an important role as a source of 2-deoxyribose 5-phosphate for deoxynucleotide synthesis in rat liver
5168
Rattus norvegicus
?
-
-
-
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.2.4
adipate
activates
Rattus norvegicus
4.1.2.4
cis-aconitate
activates
Rattus norvegicus
4.1.2.4
citrate
no activity in absence of the activator
Rattus norvegicus
4.1.2.4
DL-isocitrate
activates
Rattus norvegicus
4.1.2.4
fumarate
activates
Rattus norvegicus
4.1.2.4
Fumarate monomethyl ester
activates
Rattus norvegicus
4.1.2.4
Glutarate
activates
Rattus norvegicus
4.1.2.4
malate
activates
Rattus norvegicus
4.1.2.4
succinate
activates
Rattus norvegicus
4.1.2.4
tricarballylate
activates
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.2.4
0.17
-
2-deoxy-D-ribose 5-phosphate
-
Rattus norvegicus
4.1.2.4
0.2
-
D-glyceraldehyde 3-phosphate
-
Rattus norvegicus
4.1.2.4
0.267
-
acetaldehyde
-
Rattus norvegicus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.2.4
253000
-
monomeric form, sucrose density gradient centrifugation
Rattus norvegicus
4.1.2.4
535000
-
dimeric form, sucrose density gradient centrifugation
Rattus norvegicus
4.1.2.4
700000
-
trimeric form, sucrose density gradient centrifugation
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
Rattus norvegicus
the enzyme may have an important role as a source of 2-deoxyribose 5-phosphate for deoxynucleotide synthesis in rat liver
?
-
-
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.1.2.4
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.1.2.4
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4.1.2.4
1.775
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.2.4
2-deoxy-D-ribose 5-phosphate
-
5168
Rattus norvegicus
D-glyceraldehyde 3-phosphate + acetaldehyde
-
5168
Rattus norvegicus
-
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
-
5168
Rattus norvegicus
2-Deoxy-D-ribose 5-phosphate
-
5168
Rattus norvegicus
-
4.1.2.4
D-Glyceraldehyde 3-phosphate + acetaldehyde
the enzyme may have an important role as a source of 2-deoxyribose 5-phosphate for deoxynucleotide synthesis in rat liver
5168
Rattus norvegicus
?
-
-
-
-