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Literature summary extracted from

  • Stoffel, W.; Grol, M.
    Chemistry and biochemistry of 1-desoxysphinganine 1-phosphonate (dihydrosphingosine-1-phosphonate) (1974), Chem. Phys. Lipids, 13, 372-388.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.27 deoxysphinganine 1-phosphonate competitive Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.2.27 0.016
-
sphinganine 1-phosphate
-
Rattus norvegicus
4.1.2.27 0.016
-
deoxysphinganine 1-phosphonate
-
Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.2.27 microsome
-
Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.27 Rattus norvegicus
-
-
-
4.1.2.27 Tetrahymena pyriformis
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
4.1.2.27 Sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde possible reaction mechanism for the enzyme Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.2.27 liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.27 Dihydrosphingosine 1-phosphonate 1-deoxysphinganine 1-phosphonate Rattus norvegicus Aminoethylphosphonate + palmidaldehyde
-
?
4.1.2.27 eicosadihydrosphingosine 1-phosphate + H2O
-
Rattus norvegicus hexadecanal + 2-(icosanoylamino)ethyl phosphate
-
?
4.1.2.27 sphinganine 1-phosphate
-
Rattus norvegicus phosphoethanolamine + palmitaldehyde
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.2.27 pyridoxal 5'-phosphate
-
Rattus norvegicus
4.1.2.27 pyridoxal 5'-phosphate
-
Tetrahymena pyriformis