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Literature summary extracted from

  • Szumilo, T.
    Separation and some properties of D-galactonate pathway enzymes from Mycobacterium sp. 607 (1983), Acta Microbiol. Pol., 32, 47-52.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.21 PCMB 0.5 mM, 25% inhibition Mycobacterium sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.2.21 105000
-
 gel filtration Mycobacterium sp.
4.2.1.6 270000
-
-
 Mycobacterium sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.6 D-galactonate Mycobacterium sp. enzyme of D-galactonate catabolism ?
-
 ?
4.2.1.6 D-galactonate Mycobacterium sp. 607 enzyme of D-galactonate catabolism ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.21 Mycobacterium sp.
-
-
-
4.1.2.21 Mycobacterium sp. 607
-
-
-
4.2.1.6 Mycobacterium sp.
-
-
-
4.2.1.6 Mycobacterium sp. 607
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.21 2-dehydro-3-deoxy-D-galactonate 6-phosphate
-
 Mycobacterium sp. pyruvate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.21 2-dehydro-3-deoxy-D-galactonate 6-phosphate
-
 Mycobacterium sp. 607 pyruvate + D-glyceraldehyde 3-phosphate
-
 ?
4.2.1.6 D-galactonate enzyme of D-galactonate catabolism Mycobacterium sp. ?
-
 ?
4.2.1.6 D-galactonate enzyme of D-galactonate catabolism Mycobacterium sp. 607 ?
-
 ?
4.2.1.6 D-galactonate
-
 Mycobacterium sp. 2-dehydro-3-deoxy-D-galactonate + H2O
-
 ?
4.2.1.6 D-galactonate
-
 Mycobacterium sp. 607 2-dehydro-3-deoxy-D-galactonate + H2O
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.1.2.21 55
-
 1 min, stable up to Mycobacterium sp.
4.1.2.21 60
-
 1 min, about 10% loss of activity Mycobacterium sp.
4.1.2.21 65
-
 1 min, about 80% loss of activity Mycobacterium sp.
4.1.2.21 70
-
 1 min, complete loss of activity Mycobacterium sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.2.21 7.5 7.8
-
 Mycobacterium sp.
4.2.1.6 8
-
-
 Mycobacterium sp.

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.2.21 6.3 9 pH 6.3: about 75% of maximal activity, pH 9.0: about 30% of maximal activity Mycobacterium sp.