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Literature summary extracted from

  • Ghalambor, M.A.; Heath, E.C.
    The metabolism of L-fucose. II. The enzymatic cleavage of L-fuculose 1-phosphate (1962), J. Biol. Chem., 237, 2427-2433.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.17 EDTA
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.2.17 0.7
-
 L-Fuculose 1-phosphate
-
 Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.2.17 Ca2+ divalent cation required Escherichia coli
4.1.2.17 Ca2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli
4.1.2.17 Mg2+ divalent cation required Escherichia coli
4.1.2.17 Mg2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli
4.1.2.17 Mn2+ divalent cation required Escherichia coli
4.1.2.17 Mn2+ 0.01 M, restores activity after dialysis with EDTA Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.17 L-Fuculose 1-phosphate Escherichia coli initial step in the metabolism of L-fucose ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.17 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.17
-
 Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.2.17 additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.17 6-Deoxy-L-sorbose 1-phosphate about 5% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
4.1.2.17 D-Fructose 1,6-diphosphate about 4% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
4.1.2.17 D-Fructose 1-phosphate about 4% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
4.1.2.17 D-Ribulose 1,5-diphosphate about 6% of the activity with L-fuculose 1-phosphate Escherichia coli ?
-
 ?
4.1.2.17 Glycerone phosphate + (R)-lactaldehyde at 73% of the activity with (S)-lactaldehyde Escherichia coli 6-Deoxy-D-psicose 1-phosphate
-
 ?
4.1.2.17 Glycerone phosphate + (S)-lactaldehyde
-
 Escherichia coli L-Fuculose 1-phosphate
-
 ?
4.1.2.17 glycerone phosphate + D-glyceraldehyde at 33% of the activity with (S)-lactaldehyde Escherichia coli D-psicose 1-phosphate
-
 ?
4.1.2.17 Glycerone phosphate + glycolaldehyde at 10% of the activity with (S)-lactaldehyde Escherichia coli D-Ribulose 1-phosphate
-
 ?
4.1.2.17 glycerone phosphate + L-glyceraldehyde at 33% of the activity with (S)-lactaldehyde Escherichia coli L-tagatose 1-phosphate
-
 ?
4.1.2.17 L-fuculose 1-phosphate
-
 Escherichia coli glycerone phosphate + (S)-lactaldehyde
-
 ?
4.1.2.17 L-Fuculose 1-phosphate initial step in the metabolism of L-fucose Escherichia coli ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.2.17 7.2
-
-
 Escherichia coli

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.2.17 6.4 8.8 pH 6.4: about 30% of maximal activity, pH 8.8: about 40% of maximal activity Escherichia coli