EC Number | Application | Comment | Organism |
---|---|---|---|
4.2.3.17 | medicine | chemotherapeutic agent against a range of cancers, including ovarian and breast cancer | Taxus brevifolia |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.3.17 | 0.0026 | - |
geranylgeranyl diphosphate | - |
Taxus canadensis | |
4.2.3.17 | 0.025 | - |
Mg2+ | cofactor Mg2+ | Taxus canadensis |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.17 | Mg2+ | - |
Taxus canadensis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.3.17 | 79000 | - |
79000, SDS-PAGE | Taxus canadensis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.17 | geranylgeranyl diphosphate | Taxus brevifolia | catalyzes the first step in taxol biosynthesis | taxa-4,11-diene + diphosphate | - |
? | |
4.2.3.17 | geranylgeranyl diphosphate | Taxus canadensis | catalyzes the first step in taxol biosynthesis | taxa-4,11-diene + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.3.17 | Taxus brevifolia | - |
- |
- |
4.2.3.17 | Taxus canadensis | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.2.3.17 | - |
Taxus canadensis |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.2.3.17 | 0.0003 | - |
- |
Taxus canadensis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.17 | geranylgeranyl diphosphate | - |
Taxus brevifolia | taxa-4(5),11(12)-diene + diphosphate | - |
? | |
4.2.3.17 | geranylgeranyl diphosphate | - |
Taxus canadensis | taxa-4(5),11(12)-diene + diphosphate | - |
? | |
4.2.3.17 | geranylgeranyl diphosphate | catalyzes the first step in taxol biosynthesis | Taxus brevifolia | taxa-4,11-diene + diphosphate | - |
? | |
4.2.3.17 | geranylgeranyl diphosphate | catalyzes the first step in taxol biosynthesis | Taxus canadensis | taxa-4,11-diene + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.3.17 | ? | 79000, SDS-PAGE | Taxus canadensis |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.3.17 | 8.5 | - |
- |
Taxus canadensis |