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Literature summary extracted from

  • Buehrer, B.M.; Bell, R.M.
    Inhibition of sphingosine kinase in vitro and in platelets. Implications for signal transduction pathways (1992), J. Biol. Chem., 267, 3154-3159.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.91 D(+)threo-Sphinganine
-
 Rattus norvegicus
2.7.1.91 dihydrosphingosine L-erythro-, L-threo- and D-threo-isomer Rattus norvegicus
2.7.1.91 L(-)threo-Sphinganine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.91 microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.91 ATP + sphinganine Rattus norvegicus D-erythro-sphinganine, sphingosine metabolism ADP + sphinganine 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.91 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.91 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.91 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.91 ATP + sphinganine D-erythro-sphinganine, sphingosine metabolism Rattus norvegicus ADP + sphinganine 1-phosphate
-
 ?