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Literature summary extracted from

  • Jennissen, H.P.; Petersen-von Gehr, J.K.H.; Botzet, G.
    Activation and inhibition of phosphorylase kinase by monospecific antibodies against preparatively isolated alpha, beta and gamma subunits (1985), Eur. J. Biochem., 147, 619-630.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.19 Monospecific antibodies against alpha, beta and gamma subunits mechanism, kinetic, anti-beta subunit reverses inhibition by anti-alpha at pH 6.8 Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.11.19 additional information
-
 additional information influence of anti-subunit antibodies Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.19 Mg2+ requirement Oryctolagus cuniculus
2.7.11.19 Mg2+ major role of Mg2+: cosubstrate in Mg2+-ATP complex Oryctolagus cuniculus
2.7.11.19 phosphate requirement, phosphate containing enzyme Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.19 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.19 homogenous alpha, beta and gamma subunits Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.19 skeletal muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.19 ATP + phosphorylase b cosubstrate: Mg-ATP complex Oryctolagus cuniculus ADP + phosphorylase a
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.19 More amino acid composition of alpha Oryctolagus cuniculus
2.7.11.19 More gamma Oryctolagus cuniculus
2.7.11.19 More beta Oryctolagus cuniculus